We have located links that may give you full text access.
Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Sleep apnea in acute coronary syndrome: high prevalence but low impact on 6-month outcome.
Sleep Medicine 2006 September
BACKGROUND AND PURPOSE: We postulate that the prevalence of sleep-disordered breathing (SDB) in subjects admitted with acute coronary syndrome (ACS) is high, self-report of SDB symptoms is helpful in identifying patients with ACS at risk for SDB, and prospective risk for adverse ACS outcomes is associated with SDB.
PATIENTS AND METHODS: Consecutive patients admitted to the VA hospital with ACS over approximately 1 year were invited to participate. The Cleveland sleep habits questionnaire was administered, and a portable sleep study (Eden-trace, Level 3 monitoring) was performed within 72h of admission.
RESULTS: Of 104 patients with complete and adequate sleep studies, 66.4% had an apnea-hypopnea index (AHI) >10/h, and 26.0%, an AHI>30 with the prevalent apnea pattern being obstructive (72.1%). Neither pre-test probability for sleep apnea per questionnaire (P=0.67) nor degree of subjective sleepiness (P=0.83) predicted SDB. Although symptoms of dyspnea and paroxysmal nocturnal dyspnea were significantly higher in SDB (AHI> or =10) compared to non-SDB (AHI<10) 6 months after admission for ACS, odds of readmission were not significantly different, and this lack of association persisted after covariate adjustment. The factors predicating readmission, but only at 1 month, were age and diabetes.
CONCLUSIONS: In the setting of ACS, the prevalence of SDB was very high in this population and was not detected by self-reports of sleepiness or composite risk for SDB. The odds of adverse outcome for ACS up to 6 months were no different in patients with SDB compared to those without SDB, as compared to effects of an older age or presence of diabetes.
PATIENTS AND METHODS: Consecutive patients admitted to the VA hospital with ACS over approximately 1 year were invited to participate. The Cleveland sleep habits questionnaire was administered, and a portable sleep study (Eden-trace, Level 3 monitoring) was performed within 72h of admission.
RESULTS: Of 104 patients with complete and adequate sleep studies, 66.4% had an apnea-hypopnea index (AHI) >10/h, and 26.0%, an AHI>30 with the prevalent apnea pattern being obstructive (72.1%). Neither pre-test probability for sleep apnea per questionnaire (P=0.67) nor degree of subjective sleepiness (P=0.83) predicted SDB. Although symptoms of dyspnea and paroxysmal nocturnal dyspnea were significantly higher in SDB (AHI> or =10) compared to non-SDB (AHI<10) 6 months after admission for ACS, odds of readmission were not significantly different, and this lack of association persisted after covariate adjustment. The factors predicating readmission, but only at 1 month, were age and diabetes.
CONCLUSIONS: In the setting of ACS, the prevalence of SDB was very high in this population and was not detected by self-reports of sleepiness or composite risk for SDB. The odds of adverse outcome for ACS up to 6 months were no different in patients with SDB compared to those without SDB, as compared to effects of an older age or presence of diabetes.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app