Antihyperglycemic effect of Cucurbita ficifolia fruit extract in streptozotocin-induced diabetic rats

Tao Xia, Qin Wang
Fitoterapia 2006, 77 (7): 530-3
In the present study, the antihyperglycemic effects of Cucurbita ficifolia fruit extract were investigated on streptozotocin-induced experimental diabetes in rats. Oral administration of the extract (300 and 600 mg/kg body weight, day) for 30 days resulted in a significant reduction in blood glucose, glycosylated haemoglobin, and an increase in plasma insulin and total haemoglobin. The effect was compared with 150 mg/kg b.w. tolbutamide.

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