[Psychotropic effects of diazepam in male mice with alternative psycho-emotional statuses]

A V Amikishieva, S N Semendiaeva
Rossiĭskii Fiziologicheskiĭ Zhurnal Imeni I.M. Sechenova 2006, 92 (4): 488-98
Effects of diazepam (0.1, 0.5 and 1 microg/kg, i. p.) on communicative, anxious behaviors, exploratory activities and sexual motivation of C57BL/6J male mice with alternative psychoemotional statuses (intact and anxious) were studied. Increased level on anxiety was formed by sensory contacts technique. Behavioral effects of diazepam depend on initial psycho-emotional status of animals. The compound has an anxiolytic effect in new situation on anxious males but does not have it in situation of social contacts. Diazepam reinforces initial sexual interest in anxious mice; however, it does not enable correct exhaustion of sexual motivation. Furthermore, the compound provokes development of the exhaustion in intact male mice.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"