Fufang cangzhu tang for treatment of senile obesity or overweight complicated with impaired glucose tolerance --a clinical observation in 32 cases.

OBJECTIVE: To observe the therapeutic effect of Fufang Cangzhu Tang (Composite Atractylodes Decoction) on senile obesity or overweight with impaired glucose tolerance (IGT).

METHODS: 32 cases of senile obesity or overweight with IGT were treated with Composite Atractylodes Decoction, with another 30 cases treated with dimethyldiguanide as the controls. Changes of body weight, waist circumference, hip circumference, waist hip circumference ratio (WHR), glucose tolerance, fast serum insulin and blood lipid before and after treatment were compared.

RESULTS: After treatment, the body weight, waist circumference, hip circumference and WHR, glucose tolerance, fast serum insulin and blood lipid in the Composite Atractylodes Decoction treatment group decreased significantly (P < 0.05 or P < 0.01), with no significant difference as compared with the control group (P > 0.05).

CONCLUSION: Composite Atractylodes Decoction can obviously decrease the body weight, waist circumference, hip circumference, WHR, glucose tolerance, fast serum insulin and blood lipid in the senile patients with obesity or overweight with impaired glucose tolerance.