We have located links that may give you full text access.
Evaluation Studies
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
A surface-modified sperm sorting device with long-term stability.
Biomedical Microdevices 2006 June
Microfluidic devices fabricated from poly (dime- thylsiloxane) (PDMS) offer the ability to improve our biological and medical capabilities. Although PDMS offers a range of intriguing benefits for biomedical applications, the intrinsically hydrophobic nature of PDMS may impede with the tremendous potential of these devices. Here, we describe a PDMS-based sperm sorting device, which has been surface-modified via graft-co-polymerization of poly(ethylene glycol) methyl ether methacrylate to create a moderately hydrophilic and non-fouling surface. This process involves the exposure of PDMS to UV/ozone, which activates the PDMS surface to bond to the substrate and, at the same time, initiates the graft-co-polymerization from the PDMS surface. In this study, we confirmed long-term stability of surface-modified PDMS for up to 56 days based on Fourier transformation infrared spectroscopy (FTIR), contact angle measurements, and protein adsorption studies. Moreover, the applicability of our method to PDMS-based sperm sorting devices was demonstrated by successfully sorting human sperm.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app