JOURNAL ARTICLE

Intracytoplasmic sperm injection may lead to vertical transmission, expansion, and de novo occurrence of Y-chromosome microdeletions in male fetuses

Sook-Hwan Lee, So-Yeon Ahn, Kyo-Won Lee, KyuBum Kwack, Hye-Sun Jun, Kwang-Yul Cha
Fertility and Sterility 2006, 85 (5): 1512-5
16566932
Y-chromosome microdeletion in male fetuses conceived by intracytoplasmic sperm injection (ICSI) was screened by polymerase chain reaction for sequence-tagged sites in azoospermia factor (AZF)-b and AZFc regions. Treatment with ICSI may lead to vertical transmission, expansion, and de novo Y-chromosome microdeletion in male fetuses.

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