Oral alendronate therapy for severe vitamin D intoxication of the infant with nephrocalcinosis

Mehmet Emre Atabek, Ozgur Pirgon, Ahmet Sert
Journal of Pediatric Endocrinology & Metabolism: JPEM 2006, 19 (2): 169-72
Vitamin D intoxication is a well-known cause of hypercalcemia in children. We report here the use of oral alendronate for the treatment of hypercalcemia due to vitamin D intoxication in a 7 month-old infant with nephrocalcinosis. The serum calcium levels were normalized without complications. Oral alendronate therapy may be safely used in hypercalcemia due to vitamin. D intoxication in pediatric patients with nephrocalcinosis resistant to hydration, diuretics or corticosteroids.

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