We have located links that may give you full text access.
Comparative Study
Journal Article
Comparison of peritoneal dialysis and haemodialysis after renal transplant failure.
Nephrology, Dialysis, Transplantation 2006 June
BACKGROUND: A growing number of patients are returning to dialysis after renal transplant failure. The aim of this study is to determine whether peritoneal dialysis (PD) is a safe and good treatment option for these patients.
METHODS: All patients returning to PD or haemodialysis (HD) after renal transplant failure before 1 October 2002 at the University Hospital Gasthuisberg, Leuven, Belgium, were evaluated. Data were collected until death, retransplantation (reTx), transfer to HD or PD or until 1 January 2003.
RESULTS: Twenty-one patients starting PD (PDpostTx-group) and 39 patients starting HD (HDpostTx-group) after renal transplant failure were included in the study. There were no significant differences in age, sex, serum albumin- and CRP-levels at baseline. The total time on renal replacement therapy at transplant failure and time to transplant failure did not differ between the two groups either. Furthermore, the baseline comorbidity was similar in both groups. During follow-up, the outcome did not differ significantly between the two groups. However, there was a tendency towards higher patient survival and reTx tended to be more frequent in the PDpostTx-group. Moreover, patients in the HDpostTx-group tended to accrue more new comorbidity. The incidence of peritonitis and the evolution of dialysis adequacy (renal and peritoneal Kt/V and creatinine clearances) with time in the PDpostTx-group was similar to that seen in our centre's PD patients who had never undergone transplantation before.
CONCLUSIONS: This study suggests that the outcome in patients starting PD after renal transplant failure is at least as good as the outcome in those starting HD. Although these observational findings warrant further confirmation, PD therefore can be regarded as a safe and good treatment option for patients returning to dialysis after renal transplant failure.
METHODS: All patients returning to PD or haemodialysis (HD) after renal transplant failure before 1 October 2002 at the University Hospital Gasthuisberg, Leuven, Belgium, were evaluated. Data were collected until death, retransplantation (reTx), transfer to HD or PD or until 1 January 2003.
RESULTS: Twenty-one patients starting PD (PDpostTx-group) and 39 patients starting HD (HDpostTx-group) after renal transplant failure were included in the study. There were no significant differences in age, sex, serum albumin- and CRP-levels at baseline. The total time on renal replacement therapy at transplant failure and time to transplant failure did not differ between the two groups either. Furthermore, the baseline comorbidity was similar in both groups. During follow-up, the outcome did not differ significantly between the two groups. However, there was a tendency towards higher patient survival and reTx tended to be more frequent in the PDpostTx-group. Moreover, patients in the HDpostTx-group tended to accrue more new comorbidity. The incidence of peritonitis and the evolution of dialysis adequacy (renal and peritoneal Kt/V and creatinine clearances) with time in the PDpostTx-group was similar to that seen in our centre's PD patients who had never undergone transplantation before.
CONCLUSIONS: This study suggests that the outcome in patients starting PD after renal transplant failure is at least as good as the outcome in those starting HD. Although these observational findings warrant further confirmation, PD therefore can be regarded as a safe and good treatment option for patients returning to dialysis after renal transplant failure.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app