A 10-year study of squamous cell carcinoma in Hamedan in the west of Iran (1993-2002).

BACKGROUND: Cutaneous squamous cell carcinoma (SCC) is the second most common form of skin cancer in Caucasians. Environmental factors, especially sunlight, play an important role in its pathogenesis. Aim To better define the frequency and characteristics of SCC in patients biopsied at Hamedan Sina Hospital in the west of Iran.

METHODS: This descriptive cross-sectional study was carried out in patients diagnosed with SCC in the Department of Dermatology, Hamedan Sina Hospital, Hamedan, Iran, in the 10-year period from 1993 to 2002.

RESULTS: From a total of 6846 biopsies, 669 skin cancers were diagnosed, including 449 (66.67%) basal cell carcinomas (BCC) and 179 (26.76%) SCC. The head and face were the most common sites of SCC location. Farming was the most common occupation.

CONCLUSION: SCC is the second most common form of skin malignancy in the west of Iran. Sunlight may play a role in the etiology of this tumor.