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Bilirubin oxidase activity of Bacillus subtilis CotA.

Shin-ichi Sakasegawa, Hidehiko Ishikawa, Shigeyuki Imamura, Haruhiko Sakuraba, Shuichiro Goda, Toshihisa Ohshima
Applied and Environmental Microbiology 2006 January
The spore coat protein CotA from Bacillus subtilis was previously identified as a laccase. We have now found that CotA also shows strong bilirubin oxidase activity and markedly higher affinity for bilirubin than conventional bilirubin oxidase. This is the first characterization of bilirubin oxidase activity in a bacterial protein.

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