JOURNAL ARTICLE

A twin-family study of the association between employment, burnout and anxious depression

Christel M Middeldorp, Danielle C Cath, Dorret I Boomsma
Journal of Affective Disorders 2006, 90 (2): 163-9
16337278

BACKGROUND: Earlier studies have shown that employment and burnout are related to anxiety and depression. This twin-family study investigates to what extent these associations are caused by shared etiological factors.

METHODS: In a sample of 4,309 Dutch twins and 1,008 siblings, bivariate genetic analyses of employment and anxious depression and of burnout and anxious depression were carried out using structural equation modelling.

RESULTS: Employment and anxious depression were both influenced by genetic and individual-specific environmental factors. The association between employment and anxious depression was small, but significant, estimated at -0.08. Power was too low to decide whether the covariance was explained by genetic or environmental factors. In burnout, familial clustering was due to genetic factors in men, but to genetic and common environmental factors in women. In both sexes, there was a strong correlation of around 0.40 with anxious depression, which was explained by shared genetic and shared individual-specific environmental factors.

LIMITATIONS: The group of unemployed subjects in our sample not only contained subjects who were searching for a job, but also subjects who were out of the labour force.

CONCLUSIONS: Associations between employment and anxious depression as well as between burnout and anxious depression are due to overlapping genetic and individual-specific environmental factors. Work related circumstances, e.g. financial strain or work-family conflict, might be of importance in burnout and anxious depression. These results support the notion that a genetic vulnerability for depression also increases the risk for exposure to high-risk environments, such as unemployment.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read
16337278
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"