JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
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Disease severity in children and adults with Pompe disease related to age and disease duration.

Neurology 2005 June 29
Information about 255 children and adults with Pompe disease was gathered through a questionnaire. Disease severity was associated with disease duration and not with age; an early manifestation of the disease implied earlier wheelchair or ventilator dependency. The patient group under age 15 included a subgroup with a more severe and rapid course of the disease. They require more intensive follow-up and early intervention, before irreversible damage has occurred.

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