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Cerebral Whipple's disease as a cause of reversible dementia.

T Rossi, R Haghighipour, M Haghighi, S Paolini, O Scarpino
Clinical Neurology and Neurosurgery 2005 April
We describe a case of reversible dementia caused by Tropheryma whippelii (TW). Diagnosis was confirmed by a positive polymerase chain reaction for this pathogen both on serum and cerebrospinal fluid. Specific antibiotic therapy resulted in distinct clinical and neuroradiological improvement. Control polymerase chain reaction for T. whippelii on serum and cerebrospinal fluid was negative.

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