National survey of patients with hemophilia and other congenital bleeding disorders in Thailand

Ampaiwan Chuansumrit, Chularatana Mahasandana, Yingyong Chinthammitr, Boonchu Pongtanakul, Vichai Laossombat, Weerasak Nawarawong, Yuchinda Lektakul, Somporn Wangruangsatid, Ladda Sriboriboonsin, Ponlapat Rojnakarin, Pantep Angchaisuksiri et al.
Southeast Asian Journal of Tropical Medicine and Public Health 2004, 35 (2): 445-9
A national survey of patients with hemophilia and other congenital bleeding disorders in Thailand was conducted in the years 2000 to 2002. Questionnaires were sent to physicians working at hospitals throughout the country. Although the overall response rate to the questionnaires was 19%, the two highest rates of 80% and 73.7% were found at university and regional hospitals, respectively, where most of the patients received their diagnosis and treatment. A total of 1,450 patients comprised of hemophilia 1,325 cases, von Willebrand disease, 69 cases, congenital factor VII deficiency, 15 cases, hereditary platelet dysfunction, 22 cases, and undefined causes of congenital bleeding disorders, 19 cases. Most were pediatric patients <15 years of age. Treatment was mainly given on demand for a bleeding episode, while only 8.6% received additional home treatment for early bleeding episodes. Replacement therapy primarily relied on fresh frozen plasma, cryoprecipitate and cryo-removed plasma. Factor concentrate was seldom used because of the high price. As a result, hemophilia care services in Thailand should be strengthened by providing comprehensive education for medical personnel, making available simple laboratory kits to determine hemophilia A and B, ensuring an adequate supply of blood components and affordable factor concentrate, and establishing home care treatment.


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