Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

Jun Cheng, Jiangtao Xie, Xianjin Luo
Bioorganic & Medicinal Chemistry Letters 2005 January 17, 15 (2): 267-9
Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B(3) in VERO cells. Some structure-activity relationships were discussed.

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