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Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives.

Jun Cheng, Jiangtao Xie, Xianjin Luo
Bioorganic & Medicinal Chemistry Letters 2005 January 18
Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B(3) in VERO cells. Some structure-activity relationships were discussed.

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