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CLINICAL TRIAL
COMPARATIVE STUDY
ENGLISH ABSTRACT
JOURNAL ARTICLE
[Buprenorphine or methadone for detoxification of young opioid addicts?].
Psychiatrische Praxis 2004 November
OBJECTIVE: Comparison of buprenorphine vs. methadone to determine which medication is better for the detoxification of young opioid addicts.
METHOD: 93 consecutive opioid-dependent patients (ICD-10) from an in-patient detoxification unit for adolescents were investigated, of which 42 chose buprenorphine and 51 chose methadone for detoxification. Both groups did not differ with regard to different sociodemographic and addiction-specific variables such as age, gender, initiation of drug consumption and duration of opioid intake.
RESULTS: 23.5 % of the methadone patients and 38.1 % of the buprenorphine patients finished detoxification successfully, in addition the buprenorphine patients finished detoxification 1.62 days earlier. There was no significant difference concerning these items.
CONCLUSION: Buprenorphine seems to be at least as effective as methadone for opioid withdrawal in young addicts.
METHOD: 93 consecutive opioid-dependent patients (ICD-10) from an in-patient detoxification unit for adolescents were investigated, of which 42 chose buprenorphine and 51 chose methadone for detoxification. Both groups did not differ with regard to different sociodemographic and addiction-specific variables such as age, gender, initiation of drug consumption and duration of opioid intake.
RESULTS: 23.5 % of the methadone patients and 38.1 % of the buprenorphine patients finished detoxification successfully, in addition the buprenorphine patients finished detoxification 1.62 days earlier. There was no significant difference concerning these items.
CONCLUSION: Buprenorphine seems to be at least as effective as methadone for opioid withdrawal in young addicts.
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