Anagrelide-associated cardiomyopathy in polycythemia vera and essential thrombocythemia

Donald J Jurgens, Alvaro Moreno-Aspitia, Ayalew Tefferi
Haematologica 2004, 89 (11): 1394-5
A comprehensive database inquiry at our institutions identified 11 patients with echocardiogram-documented idiopathic cardiomyopathy that post-dated a diagnosis of either polycythemia vera or essential thrombocythemia. Anagrelide therapy was temporally associated with the particular complication in 6 patients, all of whom experienced symptomatic and/or objective improvement after drug discontinuation.

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