JOURNAL ARTICLE

The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism

E Virginia Armbrust, John A Berges, Chris Bowler, Beverley R Green, Diego Martinez, Nicholas H Putnam, Shiguo Zhou, Andrew E Allen, Kirk E Apt, Michael Bechner, Mark A Brzezinski, Balbir K Chaal, Anthony Chiovitti, Aubrey K Davis, Mark S Demarest, J Chris Detter, Tijana Glavina, David Goodstein, Masood Z Hadi, Uffe Hellsten, Mark Hildebrand, Bethany D Jenkins, Jerzy Jurka, Vladimir V Kapitonov, Nils Kröger, Winnie W Y Lau, Todd W Lane, Frank W Larimer, J Casey Lippmeier, Susan Lucas, Mónica Medina, Anton Montsant, Miroslav Obornik, Micaela Schnitzler Parker, Brian Palenik, Gregory J Pazour, Paul M Richardson, Tatiana A Rynearson, Mak A Saito, David C Schwartz, Kimberlee Thamatrakoln, Klaus Valentin, Assaf Vardi, Frances P Wilkerson, Daniel S Rokhsar
Science 2004 October 1, 306 (5693): 79-86
15459382
Diatoms are unicellular algae with plastids acquired by secondary endosymbiosis. They are responsible for approximately 20% of global carbon fixation. We report the 34 million-base pair draft nuclear genome of the marine diatom Thalassiosira pseudonana and its 129 thousand-base pair plastid and 44 thousand-base pair mitochondrial genomes. Sequence and optical restriction mapping revealed 24 diploid nuclear chromosomes. We identified novel genes for silicic acid transport and formation of silica-based cell walls, high-affinity iron uptake, biosynthetic enzymes for several types of polyunsaturated fatty acids, use of a range of nitrogenous compounds, and a complete urea cycle, all attributes that allow diatoms to prosper in aquatic environments.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read
15459382
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"