COMPARATIVE STUDY
JOURNAL ARTICLE

[Non-invasive ventilation in chronic obstructive pulmonary disease patients with acute respiratory hypercapnic failure in a conventional hospital ward]

F J González Barcala, C Zamarrón Sanz, M Salgueiro Rodríguez, J R Rodríguez Suárez
Anales de Medicina Interna: Organo Oficial de la Sociedad Española de Medicina Interna 2004, 21 (8): 373-7
15373719

OBJECTIVE: To analyze chronic obstructive lung disease (COPD) subjects in acute hypercapnic failure who were treated with non-invasive mechanical ventilation in a general respiratory ward.

METHODS: This was a two-year prospective study of 35 patients with acute exacerbation of COPD and mean FEV1/FVC relation in stable condition of 55.3 +/- 14.8% of predicted that were treated with positive pressure respiration using a facemask in a general respiratory ward. 17 (48.5%) receive long-term oxygen therapy. Analysis was made of blood gases, before and after treatment of non-invasive ventilation, complications, and failure during treatment.

RESULTS: A significant improvement in blood gases was observed 24 hours after non-invasive ventilation treatment. The mean hospital stay was of 15.0 +/- 9.1 days and failures were registered in 3 cases (8.5%). Facial scares were the most common complication (13 patients) but it was possible to continue treatment.

CONCLUSIONS: Non-invasive ventilation is a viable treatment for patients with chronic obstructive lung disease and acute hypercapnic failure being treated in a general respiratory ward.

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