Germacranolides from Anvillea radiata

B El Hassany, F El Hanbali, M Akssira, F Mellouki, A Haidour, A F Barrero
Fitoterapia 2004, 75 (6): 573-6
The aerial parts of Anvillea radiata yielded a new germacranolide, 8alpha,9alpha-epoxyparthenolide (3), together with two known compounds, 9alpha-hydroxyparthenolide (1) and parthenolid-9-one (2). The structures of the compounds were elucidated from IR, HRMS, 1H and 13C-NMR, COSY, HETCOR, HMBC and HOHAHA spectral data. The major component 1 was tested for its cytotoxicity and antibacterial activity.

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