Antibacterial activity and cytotoxicity of extractives from Ravenia spectabilis

M H Sohrab, R Chowdhury, K M Rahman, C M Hasan, M A Rashid
Fitoterapia 2004, 75 (5): 510-3
A methanolic extract of Ravenia spectabilis, an isolated alkaloid, arborinine plus a fraction comprising arborinine and gamma-fagarine (VLC), showed mild to significant in vitro antibacterial activity. In a brine shrimp lethality bioassay, the extract and the fraction were found to exhibit moderate cytotoxicity having LC50 of 76.26 microg/ml and 14.98 microg/ml, respectively.

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