In vitro repellency of N,N-diethyl-3-methylbenzamide and N,N-diethylphenylacetamide analogs against Aedes aegypti and Anopheles stephensi (Diptera: Culicidae)

Mustapha Debboun, Joseph Wagman
Journal of Medical Entomology 2004, 41 (3): 430-4
Seventeen analogs of the repellent compounds N,N-diethyl-3-methylbenzamide (DEET) and N,N-diethylphenylacetamide (DEPA) were evaluated in vitro for repellency against laboratory-reared Aedes aegypti (L.) and Anopheles stephensi Liston mosquitoes by using a modified membrane blood feeding test system. The system was a valuable tool for comparing the effective concentrations of the repellent analogs. Additionally, this method used easily controlled test conditions, allowing completion of the many test replications necessary to evaluate all of the repellent analogs over a period of several years. One compound, N,N-diethyl-2-[3-(triflouromethyl)phenyl] acetamide, provided significantly better repellency than DEET against Ae. aegypti and slightly improved efficacy against An. stephensi. Eight of the analogs were as effective as or slightly more repellent than DEET against both species. Seven analogs were less effective than DEET and one compound, N,N-diethyl-3-hydroxybenzamide, was as a poor repellent. Overall, two DEPA analogs and a single DEET analog provided better repellency than DEET against both mosquito species and warrant future laboratory and field evaluation.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"