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Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
The effect of different nutritional feeds on the postprandial glucose response in healthy volunteers and patients with type II diabetes.
European Journal of Clinical Nutrition 2004 November
OBJECTIVE: Assessment of postprandial glycaemic response to four nutritional feeds with different macronutrient and fibre composition.
DESIGN: A randomized, double-blind, crossover study.
SETTING: University of Maastricht, the Netherlands.
SUBJECTS: A total of 10 healthy volunteers and 10 patients with type II diabetes.
INTERVENTIONS: Subjects received 200 kcal of four enteral nutrition products (two standard products and two diabetes-specific products). Fasting and postprandial plasma glucose were measured for 2 h. Peak glucose level and area under the curve were calculated.
RESULTS: In healthy volunteers and diabetic patients, the feed with a low carbohydrate (CHO), high monounsaturated fatty acid (MUFA) and high fibre content significantly decreased peak glucose concentration and area under the curve compared to the feeds with standard composition.
CONCLUSIONS: Special feeds with a low CHO, high MUFA and high fibre content improve glycaemic balance and therefore should be considered in diabetic patients who are in need of nutritional support.
DESIGN: A randomized, double-blind, crossover study.
SETTING: University of Maastricht, the Netherlands.
SUBJECTS: A total of 10 healthy volunteers and 10 patients with type II diabetes.
INTERVENTIONS: Subjects received 200 kcal of four enteral nutrition products (two standard products and two diabetes-specific products). Fasting and postprandial plasma glucose were measured for 2 h. Peak glucose level and area under the curve were calculated.
RESULTS: In healthy volunteers and diabetic patients, the feed with a low carbohydrate (CHO), high monounsaturated fatty acid (MUFA) and high fibre content significantly decreased peak glucose concentration and area under the curve compared to the feeds with standard composition.
CONCLUSIONS: Special feeds with a low CHO, high MUFA and high fibre content improve glycaemic balance and therefore should be considered in diabetic patients who are in need of nutritional support.
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