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Unintended smallpox vaccination of HIV-1-infected individuals in the United States military.

Sybil A Tasker, Glenn A Schnepf, Matthew Lim, Harold E Caraviello, Adam Armstrong, Mary Bavaro, Brian K Agan, Judith Delmar, Naomi Aronson, Mark R Wallace, John D Grabenstein,
Clinical Infectious Diseases 2004 May 2
We identified 10 individuals who had undiagnosed human immunodeficiency virus type 1 (HIV-1) infection at the time of smallpox vaccination. Mean CD4 cell count was 483 cells/mm3 (range, 286-751 cells/mm3), and mean log10 plasma HIV-1 RNA load was 4.13 copies/cm3 (range, 2.54-5.16 copies/cm3). All vaccinees (3 primary and 7 repeat) had a normal, robust reaction without complications. Smallpox vaccine was well-tolerated in this small series of HIV-1-infected military personnel.

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