We have located links that may give you full text access.
Comparative Study
Evaluation Studies
Journal Article
Research Support, Non-U.S. Gov't
IGT with fasting hyperglycemia is more strongly associated with microalbuminuria than IGT without fasting hyperglycemia.
Diabetes Research and Clinical Practice 2004 June
Previous studies have established that impaired glucose tolerance (IGT) patients with fasting hyperglycemia (IGT/FH: fasting plasma glucose (FPG) level 6.1-7.0 mmol/l and 2 h PG level of 7.8-11.1 mmol/l) exhibit higher insulin resistance than those with isolated IGT (FPG level <6.1 mmol/l and 2 h PG level of 7.8-11.1 mmol/l), but the association with microalbuminuria has not been determined. Here, we evaluate the prevalence of microalbuminuria in non-diabetic Japanese males 20-70 years of age. The subjects were classified into four groups based on the results of OGTT: normal glucose tolerance (NGT: n=71), impaired fasting glucose (IFG: n=24), isolated IGT (n=36), and IGT/FH (n=23). A urinary albumin-to-creatinine ratio (ACR) from 30 to 300 microg/mg creatinine was counted as microalbuminuria. The prevalence of microalbuminuria was higher in subjects with IGT/FH than in subjects with isolated IGT (26% versus 14%). Logistic regression analysis showed microalbuminuria to be more significantly associated with IGT/FH (OR=3.82, 95% CI 1.09-13.36) than with isolated IGT (OR=1.75, 95% CI 0.50-6.17). While insulin resistance (HOMA-IR) in isolated IGT was not significantly different from that in NGT, insulin resistance in IGT/FH was significantly higher (P<0.01). Regression analysis of ACR in IGT showed a significant correlation with insulin resistance (P=0.012). Accordingly, microalbuminuria is more strongly associated with IGT/FH than with isolated IGT, most likely due to the higher insulin resistance.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app