Pulmonary injury from transfusion-related acute lung injury

Patricia M Kopko, Mark A Popovsky
Clinics in Chest Medicine 2004, 25 (1): 105-11
Transfusion-related acute lung injury (TRALI) can be a life-threatening complication of transfusion. In its severe form, it is clinically indistinguishable from acute respiratory distress syndrome. Symptoms typically begin within 4 hours of transfusion. TRALI has been reported after transfusion of all plasma-containing blood components. TRALI is associated with antibodies to white blood cells and biologically active lipids in trans-fused blood components.

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