JOURNAL ARTICLE

Interferon-beta 1a and SARS coronavirus replication

Lisa E Hensley, Lisa E Fritz, Peter B Jahrling, Christopher L Karp, John W Huggins, Thomas W Geisbert
Emerging Infectious Diseases 2004, 10 (2): 317-9
15030704
A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort is under way to identify and test promising antiviral drugs. Here, we report that recombinant human interferon-beta 1a potently inhibits SARS coronavirus replication in vitro.

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