JOURNAL ARTICLE

Severe acute respiratory syndrome-associated coronavirus infection

Paul K S Chan, Margaret Ip, K C Ng, C W Chan Rickjason, Alan Wu, Nelson Lee, Timothy H Rainer, Gavin M Joynt, Joseph J Y Sung, John S Tam
Emerging Infectious Diseases 2003, 9 (11): 1453-4
14718090
Whether severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infection can be asymptomatic is unclear. We examined the seroprevalence of SARS-CoV among 674 healthcare workers from a hospital in which a SARS outbreak had occurred. A total of 353 (52%) experienced mild self-limiting illnesses, and 321 (48%) were asymptomatic throughout the course of these observations. None of these healthcare workers had antibody to SARS CoV, indicating that subclinical or mild infection attributable to SARS-CoV in adults is rare.

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