Weber Christian disease

V G Negalur, B V Negalur
Journal of the Association of Physicians of India 2003, 51: 724-5
Weber Christian disease or idiopathic lobular panniculitis is a skin condition that features recurring inflammation in the fat layer of the skin. We report a case of a 17 year old boy with Weber Christian disease as its occurence is extremely rare with only sparse case reports available, who presented with eighteen-month history off fever with chills off and on, arthralgia predominantly of the knees, ankles, wrists and elbows without swelling or gross limitation of movement. There was also swelling around the eyes and puffiness of the face with lumpy swellings on the jaw, cheeks and chin and painful lumps on the anterior abdominal wall. On examination a febrile patient with pallor, pitting edema of the legs, periorbital edema and multiple non-matted firm to hard tender swellings of the face, jaw and chin and multiple firm tender lumps in the anterior abdominal wall was noted. Investigations revealed anemia, leucopenia, raised sedimentation rate and mild rise of liver enzymes. Biopsy of the abdominal nodule demonstrated a lobular panniculitis without vasculitis as seen in Weber Christian disease.

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