OPEN IN READ APP
JOURNAL ARTICLE

Low-frequency fatigue is fibre type related and most pronounced after eccentric activity in rat medial gastrocnemius muscle

J M Rijkelijkhuizen, C J de Ruiter, P A Huijing, A de Haan
Pflügers Archiv: European Journal of Physiology 2003, 447 (2): 239-46
14508688
Effects of fibre type composition and type of contraction on low-frequency fatigue (LFF) were investigated in isolated rat medial gastrocnemius (GM) muscle. Fast oxidative or fast glycolytic GM muscle parts of anaesthetised male Wistar rats (n=18) were activated selectively by maximal electrical stimulation of the nerve after selective cutting of sub-branches. LFF was induced by a series of 40 isometric, concentric or eccentric contractions. Post exercise (55 min), the force-frequency curves differed significantly from the pre-exercise curves. Decreased forces were exerted mainly at the lower frequencies. This effect was significantly greater for glycolytic than oxidative muscle parts and following eccentric compared to isometric and concentric exercise. Seventy minutes following eccentric exercise, the relative values of the 60:200 Hz force ratios for the oxidative compared to the glycolytic parts were 65.6+/-2.2% and 43.6+/-4.6% (mean+/-SE) of the pre-fatigue values (=100%), respectively. In conclusion, for conditions of identical activation, eccentric exercise led to significantly more LFF than isometric and concentric exercise. In addition, and independent of the exercise type, fast glycolytic muscle parts were more susceptible to LFF than fast oxidative muscle parts.

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Trending Papers

Available on the App Store

Available on the Play Store
Remove bar
Read by QxMD icon Read
14508688
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"