Anti-inflammatory effect of Solanum lycocarpum fruits

G Vieira, P M Ferreira, L G Matos, E C Ferreira, W Rodovalho, P H Ferri, H D Ferreira, E A Costa
Phytotherapy Research: PTR 2003, 17 (8): 892-6
The croton oil-induced mouse ear oedema test, acetic acid-induced abdominal writhing, and carrageenan-induced peritonitis were used to study the anti-inflammatory effects of the crude ethanol extract and its alkaloid fraction from Solanum lycocarpum fruits. The alkaloid fraction induced a dose-dependent reduction in ear oedema formation and leukocyte migration, suggesting that S. lycocarpum fruits may contain steroidal alkaloids accounting for the anti-inflammatory effect of the crude ethanol extract.

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