We have located links that may give you full text access.
COMPARATIVE STUDY
JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
RESEARCH SUPPORT, U.S. GOV'T, P.H.S.
Cardiorespiratory fitness and the risk for stroke in men.
Archives of Internal Medicine 2003 July 29
BACKGROUND: Low cardiorespiratory fitness is considered to be a major public health problem. We examined the relationship of cardiorespiratory fitness, as indicated by maximum oxygen consumption VO(2)max with subsequent incidence of stroke. We also compared VO(2)max with conventional risk factors as a predictor for future strokes.
METHODS: Population-based cohort study with an average follow-up of 11 years from Kuopio and surrounding communities of eastern Finland. Of 2011 men with no stroke or pulmonary disease at baseline who participated in the study, 110 strokes occurred, of which 87 were ischemic. The VO(2)max was measured directly during exercise testing at baseline.
RESULTS: The relative risk for any stroke in unfit men VO(2)max, <25.2 mL/kg per minute) was 3.2 (95% confidence interval [CI], 1.71-6.12; P<.001; P<.001 for the trend across the quartiles); and for ischemic stroke, 3.50 (95% CI, 1.66-7.41; P =.001; P<.001 for trend across the quartiles), compared with fit men VO(2)max, >35.3 mL/kg per minute), after adjusting for age and examination year. The associations remained statistically significant after further adjustment for smoking, alcohol consumption, socioeconomic status, energy expenditure of physical activity, prevalent coronary heart disease, diabetes, systolic blood pressure, and serum low-density lipoprotein cholesterol level for any strokes or ischemic strokes. Low cardiorespiratory fitness was comparable with systolic blood pressure, obesity, alcohol consumption, smoking, and serum low-density lipoprotein cholesterol level as a risk factor for stroke.
CONCLUSIONS: Our findings show that low cardiorespiratory fitness was associated with an increased risk for any stroke and ischemic stroke. The VO(2)max was one of the strongest predictors of stroke, comparable with other modifiable risk factors.
METHODS: Population-based cohort study with an average follow-up of 11 years from Kuopio and surrounding communities of eastern Finland. Of 2011 men with no stroke or pulmonary disease at baseline who participated in the study, 110 strokes occurred, of which 87 were ischemic. The VO(2)max was measured directly during exercise testing at baseline.
RESULTS: The relative risk for any stroke in unfit men VO(2)max, <25.2 mL/kg per minute) was 3.2 (95% confidence interval [CI], 1.71-6.12; P<.001; P<.001 for the trend across the quartiles); and for ischemic stroke, 3.50 (95% CI, 1.66-7.41; P =.001; P<.001 for trend across the quartiles), compared with fit men VO(2)max, >35.3 mL/kg per minute), after adjusting for age and examination year. The associations remained statistically significant after further adjustment for smoking, alcohol consumption, socioeconomic status, energy expenditure of physical activity, prevalent coronary heart disease, diabetes, systolic blood pressure, and serum low-density lipoprotein cholesterol level for any strokes or ischemic strokes. Low cardiorespiratory fitness was comparable with systolic blood pressure, obesity, alcohol consumption, smoking, and serum low-density lipoprotein cholesterol level as a risk factor for stroke.
CONCLUSIONS: Our findings show that low cardiorespiratory fitness was associated with an increased risk for any stroke and ischemic stroke. The VO(2)max was one of the strongest predictors of stroke, comparable with other modifiable risk factors.
Full text links
Trending Papers
Monitoring Macro- and Microcirculation in the Critically Ill: A Narrative Review.Avicenna Journal of Medicine 2023 July
ANCA-associated vasculitis - Treatment Standard.Nephrology, Dialysis, Transplantation 2023 November 9
ASA Consensus-based Guidance on Preoperative Management of Patients on Glucagon-like Peptide-1 Receptor Agonists.Anesthesiology 2023 November 21
Common postbariatric surgery emergencies for the acute care surgeon: What you need to know.Journal of Trauma and Acute Care Surgery 2023 December 2
How we approach titrating PEEP in patients with acute hypoxemic failure.Critical Care : the Official Journal of the Critical Care Forum 2023 October 32
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
Read by QxMD is copyright © 2021 QxMD Software Inc. All rights reserved. By using this service, you agree to our terms of use and privacy policy.
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app