Clavicular metastasis from malignant trigeminal schwannoma

K Ganapathy, Mithra Ghosh
Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia 2003, 10 (4): 485-92
Extracranial metastasis arising from primary intracranial malignant tumours are rare. Cases documented have arisen from tumours arising from glial cells or from undifferentiated neurons. Extracranial deposits from intracranial malignant nerve sheath tumours have not been documented. This case report shows histological similarity - rhabdomyoblastic differentiation in a malignant neoplasm in the clavicle similar to that seen in a malignant trigeminal schwannoma operated earlier. Detailed immunohistochemistry confirmed similarity in histogenesis confirming that the clavicular deposit was a secondary arising from the malignant trigeminal schwanoma.

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