Topical therapy with tretinoin and ammonium lactate for acanthosis nigricans associated with obesity

Steven H Blobstein
Cutis; Cutaneous Medicine for the Practitioner 2003, 71 (1): 33-4
Acanthosis nigricans (AN) is a cutaneous marker of various underlying systemic conditions. To date, no satisfactory topical therapy for this cutaneous disorder has been described. The following is a report of the successful use of a combination of 12% ammonium lactate cream and 0.05% tretinoin cream to treat AN associated with obesity.

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