ENGLISH ABSTRACT
JOURNAL ARTICLE
REVIEW
[Digestive involvement of scleroderma].
La Revue du Praticien 2002 November 2
Digestive involvement in systemic sclerosis is frequent and serious, because it provides morbidity and fatality. From the pathophysiologic point of view, the first step could be Raynaud-associated neural dysfunction, followed by smooth muscle atrophy then irreversible muscle fibrosis. Oesophageal disorder is common with its main consequence: the occurrence of gastroesophageal reflux disease which could run into peptic erosive oesophagitis. Oesophageal manometry is the main diagnostic tool, gastrointestinal endoscopy helps to assess oesophageal mucosal inflammation and its possible sequels. Gastric involvement is rarely recognized but it is frequent in case of systematic investigation as well as small intestinal involvement which may provide a lot of complications: malabsorption, pseudoobstruction, bacterial overgrowth. At colonic level, anorectal involvement is frequent and leads to fecal incontinence and rectal prolapse. Reynold's syndrome is a special case which associates systemic sclerosis with primary biliary cirrhosis. The symptomatic treatments must be systematic and improve the disease's overall prognosis.
Full text links
Trending Papers
Fluid Resuscitation in Patients With Traumatic Brain Injury: A Comprehensive Review.Curēus 2023 August
Glycaemic Control and Weight Reduction: A Narrative Review of New Therapies for Type 2 Diabetes.Diabetes Therapy : Research, Treatment and Education of Diabetes and related Disorders 2023 September 16
Differential Diagnosis and Therapeutic Advances in Multiple Myeloma: A Review Article.Blood and Lymphatic Cancer : Targets and Therapy 2023
Intraoperative use of phenylephrine versus ephedrine and postoperative delirium: A multicenter retrospective cohort study.Anesthesiology 2023 September 20
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
Read by QxMD is copyright © 2021 QxMD Software Inc. All rights reserved. By using this service, you agree to our terms of use and privacy policy.
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app