JOURNAL ARTICLE

Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis

De-Yu Xie, Shashi B Sharma, Nancy L Paiva, Daneel Ferreira, Richard A Dixon
Science 2003 January 17, 299 (5605): 396-9
12532018
Condensed tannins (CTs) are flavonoid oligomers, many of which have beneficial effects on animal and human health. The flavanol (-)-epicatechin is a component of many CTs and contributes to flavor and astringency in tea and wine. We show that the BANYULS (BAN) genes from Arabidopsis thaliana and Medicago truncatula encode anthocyanidin reductase, which converts anthocyanidins to their corresponding 2,3-cis-flavan-3-ols. Ectopic expression of BAN in tobacco flower petals and Arabidopsis leaves results in loss of anthocyanins and accumulation of CTs.

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