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Intramucosal naevus with pseudoepitheliomatous hyperplasia in the gingiva: a case report

T Suzuki, H Kumamoto, H Nagasaka, H Kawamura, K Ooya
International Journal of Oral and Maxillofacial Surgery 2002, 31 (3): 330-3
This article describes the unusual case of an intraoral pigmented naevus with pseudoepitheliomatous hyperplasia of the gingiva. A 62-year-old man presented with an almost coal-black pigmented and partly white, spotted, dome-shaped swelling on the lingual gingiva of the mandible. Histologically, the lesion consisted of clusters of round-shaped naevus cells containing melanin granules, reactive with both S-100 immunohistochemical stain and Masson-Fontana silver stain, and pseudoinvasive squamous nests, reactive with cytokeratin. The pathogenesis of the present lesion and problems encountered in its differential diagnosis are discussed.

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