Analgesic and anti-inflammatory effects of the aqueous extract of leaves of Persea americana mill (lauraceae)

O O Adeyemi, S O Okpo, O O Ogunti
Fitoterapia 2002, 73 (5): 375-80
The aqueous extract of Persea americana leaves produced a dose-dependent inhibition of both phases of formalin pain test in mice, a reduction in mouse writhing induced by acetic acid and an elevation of pain threshold in the hot plate test in mice. The extract also produced a dose-dependent inhibition of carrageenan-induced rat paw oedema. The results obtained indicate that the extract possesses analgesic and anti-inflammatory effects.

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