JOURNAL ARTICLE

Multiple roles of Arabidopsis VRN1 in vernalization and flowering time control

Yaron Y Levy, Stéphane Mesnage, Joshua S Mylne, Anthony R Gendall, Caroline Dean
Science 2002 July 12, 297 (5579): 243-6
12114624
Arabidopsis VRN genes mediate vernalization, the process by which a long period of cold induces a mitotically stable state that leads to accelerated flowering during later development. VRN1 encodes a protein that binds DNA in vitro in a non-sequence-specific manner and functions in stable repression of the major target of the vernalization pathway, the floral repressor FLC. Overexpression of VRN1 reveals a vernalization-independent function for VRN1, mediated predominantly through the floral pathway integrator FT, and demonstrates that VRN1 requires vernalization-specific factors to target FLC.

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