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COMPARATIVE STUDY
JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Liquid chromatography-mass spectrometry analysis of propolis.
Phytochemical Analysis : PCA 2001 November
The composition of propolis, a resinous hive product collected by honeybees from various plant sources, depends on various factors such as season and vegetation of the area. Based on standards (either isolated from Brazilian propolis or reported from propolis) including chromane, diterpenes and phenolic compounds, different Brazilian propolis were analysed by LC-MS in order to determine their chemical constituents. Dicaffeoylquinic acids were detected in almost all water extracts of Brazilian propolis, whereas diterpenes, flavonoids and prenylated phenolic compounds were found in their methanol extracts. Based on the identified chemical constituents and their biological activities, it was determined that the quality of Brazilian propolis could be directly related to the phenolic constituents. Moreover, Baccharis dracunculifolia was concluded to be an important source of Brazilian propolis. Propolis samples from Peru, China and the Netherlands were also studied.
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