Pregnancy and condyloma. Evaluation about therapeutic effectiveness of laser CO2 on 115 pregnant women.

BACKGROUND: At present one of the most common pathologies of the female genital apparatus is infection from HPV. It may be present in the latent form or symptomatic with flat or condylomatous lesions. The condylomatous lesions are particularly interesting in pregnant women on account of the symptoms, complications and methods for treating such lesions. The aim of this study was to evaluate the therapeutic efficacy of laser-vaporization in genital condylomata during pregnancy.

METHODS: From March 1998 through October 2000 we used laser therapy to treat 115 pregnant women with florid genital condylomata. Treatment was given without regard to the gestation period. All the women were treated at least once. Persistent cases (failure of therapy) and recurrence (new infection) were classed according to the gestation week and site of lesion.

RESULTS: Unsuccessful therapy, evaluated on the basis of repeated treatment, was 7.83%. There was no evidence of recurrence in those who received therapy in the third trimester. There were no abortions, particular complications or intrauterine deaths.

CONCLUSIONS: We believe, that at present, the most effective treatment for condylomatoses in pregnant women is laser-vaporization.