OPEN IN READ APP
COMPARATIVE STUDY
JOURNAL ARTICLE

An evaluation of the impact of gender and age on QT dispersion in healthy subjects

H Tran, C M White, M S Chow, J Kluger
Annals of Noninvasive Electrocardiology 2001, 6 (2): 129-33
11333170

OBJECTIVES: To determine if gender, age, and gender per age category, have an impact on QT and QTc dispersion in healthy volunteers.

METHODS: This study was undertaken in 150 patients (50 per age group, 75 males, 75 females). The age groups included young (20-40 years), middle-aged (41-69 years) and elderly (> 70 years) subjects. The QT intervals on a 12 lead ECG were determined and Bazett's formula was used to derive the QTc intervals. The QT and QTc dispersion were determined by subtracting the shortest QTc interval from the longest on each 12-lead recording.

RESULTS: Males had higher QT dispersion than females (50 +/- 22 vs 42 +/- 18 ms, P = 0.017) but QTc dispersion was not significantly changed. No significant differences were seen among the different age categories for QT or QTc dispersion. In elderly subjects, males had higher QT and QTc dispersion than females (54 +/- 23 vs 42 +/-15 ms, P = 0.039 and 63 +/- 23.7 vs 48 +/- 21 ms, P = 0.032, respectively).

CONCLUSIONS: When evaluating the effect of gender in different age categories, elderly males have significantly greater QT and QTc dispersion than elderly female subjects. No other gender differences were noted for QT or QTc dispersion in the other two age categories. When evaluating a population of healthy volunteers, regardless of age, gender has an impact on QT dispersion but no significant interaction with QTc dispersion. Evaluating age without dividing the data by gender yields no significant differences in QT or QTc dispersion.

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Trending Papers

Available on the App Store

Available on the Play Store
Remove bar
Read by QxMD icon Read
11333170
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"