[Klüver-Bucy syndrome in herpetic meningoencephalitis]

S Bonno, F Raschilas, I Mari, E Pigne, J Pouchot, F De Broucker, P Vinceneux
La Presse Médicale 2001 January 27, 30 (3): 115-8

BACKGROUND: Klüver-Bucy syndrome (KBS) is an infrequent condition that includes, in its complete form, often massive amnesia, psychic blindness (so-called visual agnosia), oral tendencies, hypermetamorphosis, changes in emotional behavior and increased sexual activity. Anatomic lesions in KBS involve the temporal lobe cortex bilaterally, and the amygdala as well as temporal white matter.

CASE REPORT: A 17-year-old patient treated for herpetic meningoencephalitis developed neuropsychological signs leading to the diagnosis of Klüver-Bucy syndrome.

DISCUSSION: KBS can occur in various clinical conditions but herpetic encephalitis is the most frequent cause. KBS may be transient or partially regressive, but severe amnesia that may progress to Korsakoff syndrome is often persistent after herpetic encephalitis. Neuroleptics or carbamazepine can be used for symptomatic treatment.

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