We have located links that may give you full text access.
Lung function, haemoglobin and irreversibly sickled cells in sickle cell patients.
West African Journal of Medicine 2000 July
This study seeks to show whether there is a positive relationship between HbF, irreversibly sickled cells and several lung function parameters. Percentage haemoglobin F (%HbF), percent irreversibly sickled cells (%ISC), blood pressure (BP, mm Hg), heart rate (HR, b/min), forced vital capacity (FVC,I), timed vital capacity (FEV1, I) FEV1% and peak expiratory flow rate (PEFR, I/min) were measured in 10 sickle cell (in the steady state) and 15 non-sickle cell subjects matched by age and sex. Results showed that although the ages in both groups of subjects were similar, sickle cell anaemia (SCA) subjects had smaller stature. Diastolic BP was significantly lower while pulse pressure, %Hbf and %ISC were significantly higher in SCA subjects (P < 0.001 in each case). Predicted FVC, FEV1, and PEFR were significantly higher (P < 0.01, P < 0.01, P < 0.001 in each case) than observed values obtained from SCA subjects. Similarly, measured FVC, FEV1, and PEFR in SCA subjects were significantly lower (P < 0.001 respectively) than values obtained from non-sickle cell subjects. In SCA subjects, %HbF or %ISC correlated negatively with each of the ventilatory parameters and with each other. Similar results (except for PEFR) were obtained in the non-sickle cell subjects. The results suggest that %HbF and %ISC correlate negatively with lung function parameters in sickle cell sufferers in the steady state.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app