Complete response to topotecan of recurrent fallopian tube carcinoma

C J Dunton, J Neufeld
Gynecologic Oncology 2000, 76 (1): 128-9

OBJECTIVE: To describe the first complete response of recurrent Fallopian tube carcinoma to topotecan.

METHODS: A patient with recurrent Fallopian tube carcinoma previously treated with paclitaxel (Taxol) and carboplatin is described.

RESULTS: This patient demonstrated a complete clinical response to topotecan. Radiographic and CA-125 measurements were used to determine response. Response was noted after four cycles and a complete response demonstrated after six treatments.

CONCLUSION: Topotecan appears active in recurrent Fallopian tube carcinoma.

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