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[Autoimmune liver diseases. Part II].

Autoimmune hepatis along with primary biliary cirrhosis, primary sclerosing cholagitis and some other not classified primary hepatobiliary pathologies belong to the group of liver diseases which are believed to be caused by autoimmune reactions. The primary causes of those pathological states remain unknown. However, thanks to the recent studies in immunogenetics and on autoantigens, progress has been made in understanding the mechanisms underlying these pathologies. The results of these studies are criteria of diagnosis and treatment of those diseases. In spite of some beneficial results of immunosuppressive treatment of AIH, the disease in some cases progresses and those states are one of the classical indications for allogenic liver transplantation.

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