We have located links that may give you full text access.
ENGLISH ABSTRACT
JOURNAL ARTICLE
REVIEW
[Critical analysis of different methods used for toxicology screening in emergency laboratory].
Annales de Biologie Clinique 1999 September
Emergency analysis in toxicology is a difficult exercise. It involves in diagnosis, prognosis and the treatment of intoxication. Several methods exist in emergency screening. We have distinguished three large groups. Based on specificity: screening methods of medicament family (chemical methods and immunoassays) with benzodiazepines, tricyclic antidepressants, barbiturates and phenothiazines; complementary screening methods (thin layer chromatography and high pressure liquid chromatography) for a wider screening and finally quantitative methods (enzymatic, immunoassay, spectrometry and chromatography) specific to a molecule. The first group allows a rapid qualitative research according to medicament class but lacks specificity. The second group represented by the Remedi system, offers a larger screening of molecules but is more expensive and cannot detect classic molecules. The third group allows a precise dosage but is restricted to one molecule. We need one or the other of methods following clinical context and the type of molecule. In our laboratory, we have eliminated barbiturates and benzodiazepines research. We search only tricyclic antidepressants, salicylates and paracetamol. The Remedi system acts as a complement. It is essential to have a good knowledge of the limits and specificity of each method in order to allow the clinician to see the interpretation of the given result. The execution period and the quality of analytical result depend on dialogue between analyst and clinician before and after analysis.
Full text links
Trending Papers
A Personalized Approach to the Management of Congestion in Acute Heart Failure.Heart International 2023
Potential Mechanisms of the Protective Effects of the Cardiometabolic Drugs Type-2 Sodium-Glucose Transporter Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Heart Failure.International Journal of Molecular Sciences 2024 Februrary 21
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app