We have located links that may give you full text access.
Comparative Study
Journal Article
Effects of torsional rigidity on fracture healing: strength and mineralization in rat femora.
Journal of Orthopaedic Trauma 1999 March
OBJECTIVE: To assess the effects of torsional rigidity and dynamization on fracture healing in a medullary nailed rat femoral model.
STUDY DESIGN: Randomized study in male Wistar rats with a diaphyseal osteotomy/fracture.
METHODS: Reamed cannulated nailing was performed in sixty rats. One group (twenty rats) received unlocked nails (UL group) and another group received nails with proximal and distal locking that was dynamized after twenty days (DL group). The third group was statically locked (SL group). A fourth group of twenty rats served as the control group. After randomization, the femurs of ten rats in each group at six and twelve weeks were studied clinically, radiologically, and biomechanically, and bone mineralization was measured by dual-energy x-ray absorptiometry (DEXA).
RESULTS: Radiographs in two planes revealed clearly visible fractures at six weeks, and at twelve weeks bridging callus was apparent in all three treatment groups. The callus area in the UL group was significantly larger at six weeks than in the other groups, and at twelve weeks the UL and DL groups had larger callus areas than the SL group. Biomechanically, UL nails had reduced maximum bending load at six and twelve weeks, while DL nails had increased fracture energy at six weeks compared with SL nails. Bone mineral content and bone mineral density in the callus segment and diaphysis were increased with DL nails at six weeks.
CONCLUSION: This animal study indicates that (a) interlocked nailing has a beneficial effect on bone healing and (b) although dynamization may have a beneficial effect on the quality of early bone healing, (c) dynamization does not increase the rate of bony union. The clinical implication is that routine early dynamization of locked femoral fractures may not be indicated, reserving dynamization to cases of delayed union.
STUDY DESIGN: Randomized study in male Wistar rats with a diaphyseal osteotomy/fracture.
METHODS: Reamed cannulated nailing was performed in sixty rats. One group (twenty rats) received unlocked nails (UL group) and another group received nails with proximal and distal locking that was dynamized after twenty days (DL group). The third group was statically locked (SL group). A fourth group of twenty rats served as the control group. After randomization, the femurs of ten rats in each group at six and twelve weeks were studied clinically, radiologically, and biomechanically, and bone mineralization was measured by dual-energy x-ray absorptiometry (DEXA).
RESULTS: Radiographs in two planes revealed clearly visible fractures at six weeks, and at twelve weeks bridging callus was apparent in all three treatment groups. The callus area in the UL group was significantly larger at six weeks than in the other groups, and at twelve weeks the UL and DL groups had larger callus areas than the SL group. Biomechanically, UL nails had reduced maximum bending load at six and twelve weeks, while DL nails had increased fracture energy at six weeks compared with SL nails. Bone mineral content and bone mineral density in the callus segment and diaphysis were increased with DL nails at six weeks.
CONCLUSION: This animal study indicates that (a) interlocked nailing has a beneficial effect on bone healing and (b) although dynamization may have a beneficial effect on the quality of early bone healing, (c) dynamization does not increase the rate of bony union. The clinical implication is that routine early dynamization of locked femoral fractures may not be indicated, reserving dynamization to cases of delayed union.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app