Add like
Add dislike
Add to saved papers

SARS-CoV-2 infection may increase risk of prediabetes progression into diabetes

2 Minute Medicine 2023 June 15

1. Patients with pre-diabetes who were hospitalized with COVID-19 had a greater risk of developing type-2 diabetes mellitus, compared to hospitalized pre-diabetic patients without COVID-19. 

Evidence Rating Level: 2 (Good)

Recent observations and case reports have suggested an increased risk of developing new-onset type-2 diabetes (T2D) following COVID-19 infection. Researchers aimed to determine the incidence of new-onset diabetes following COVID-19 infection for participants with preexisting prediabetes. Data were collected from medical records using the Montefiore Health System in Bronx, New York. Researchers compared 42,877 patients with COVID-19 and a history of pre-diabetes to a propensity-matched group of 9306 pre-diabetic patients without COVID-19. Two primary outcomes were assessed: the incidence of new-onset in-hospital DM and new-onset persistent DM at a 5-month follow-up. Compared to hospitalized patients without COVID-19, hospitalized patients with COVID-19 had a greater incidence of new-onset DM (21.9% vs 6.02%, p<0.001) and persistent DM (14.75% vs 7.51%, p<0.001). The same trend was not observed for non-hospitalized patients. Researchers postulate that the physical and mental stress of hospitalization, as well as the steroids used to treat severe COVID-19 infections, may contribute to the development of DM. This study demonstrates that patients with pre-diabetes who are hospitalized for COVID-19 may benefit from more careful surveillance of their glycemic control.

Click to read the study in BMJ

Originally Published By 2 Minute Medicine®. Reused on Read by QxMD with permission.

©2023 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Add to Saved Papers

Get 1-tap access

For the best experience, use the Read mobile app

Group 7SearchHeart failure treatmentPapersTopicsCollectionsEffects of Sodium-Glucose Cotransporter 2 Inhibitors for the Treatment of Patients With Heart Failure Importance: Only 1 class of glucose-lowering agents-sodium-glucose cotransporter 2 (SGLT2) inhibitors-has been reported to decrease the risk of cardiovascular events primarily by reducingSeptember 1, 2017: JAMA CardiologyAssociations of albuminuria in patients with chronic heart failure: findings in the ALiskiren Observation of heart Failure Treatment study.CONCLUSIONS: Increased UACR is common in patients with heart failure, including non-diabetics. Urinary albumin creatininineJul, 2011: European Journal of Heart FailureRandomized Controlled TrialEffects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.Review

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

Read by QxMD is copyright © 2021 QxMD Software Inc. All rights reserved. By using this service, you agree to our terms of use and privacy policy.

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app