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JOURNAL ARTICLE
Antoine Berberi, Amine El Zoghbi, Georges Aad, Georges Tehini
AIM: The objective of this study was to assess marginal bone level around single implants inserted in fresh extraction sockets in the anterior maxillary region and instantly restored with computer-aided design/computer-aided manufacturing customized temporary crowns cemented on the final abutment. MATERIALS AND METHODS: A total of 20 patients (15 females and 5 males, with a mean age of 30 years), where 20 were placed in fresh extraction sockets. After raising a full-thickness flap, atraumatic extraction was performed the implant site was prepared and fixtures were stabilized on the palatal bone wall...
March 19, 2024: Journal of Contemporary Dental Practice
#22
REVIEW
Yoshiaki Adachi, Shigenori Kawabata
We are engaged in the development and clinical application of a neural magnetic field measurement system that utilizes biomagnetic measurements to observe the activity of the spinal cord and peripheral nerves. Unlike conventional surface potential measurements, biomagnetic measurements are not affected by the conductivity distribution within the body, making them less influenced by the anatomical structure of body tissues. Consequently, functional testing using biomagnetic measurements can achieve higher spatial resolution compared to surface potential measurements...
2024: Frontiers in medical technology
#23
JOURNAL ARTICLE
Hong-Jie Dai, Chien-Chang Chen, Tatheer Hussain Mir, Ting-Yu Wang, Chen-Kai Wang, Ya-Chen Chang, Shu-Jung Yu, Yi-Wen Shen, Cheng-Jiun Huang, Chia-Hsuan Tsai, Ching-Yun Wang, Hsiao-Jou Chen, Pei-Shan Weng, You-Xiang Lin, Sheng-Wei Chen, Ming-Ju Tsai, Shian-Fei Juang, Su-Ying Wu, Wen-Tsung Tsai, Ming-Yii Huang, Chih-Jen Huang, Chih-Jen Yang, Ping-Zun Liu, Chiao-Wen Huang, Chi-Yen Huang, William Yu Chung Wang, Inn-Wen Chong, Yi-Hsin Yang
Data curation for a hospital-based cancer registry heavily relies on the labor-intensive manual abstraction process by cancer registrars to identify cancer-related information from free-text electronic health records. To streamline this process, a natural language processing system incorporating a hybrid of deep learning-based and rule-based approaches for identifying lung cancer registry-related concepts, along with a symbolic expert system that generates registry coding based on weighted rules, was developed...
December 2024: Computational and Structural Biotechnology Journal
#24
REVIEW
Ta-Wei Tai, Hsuan-Yu Chen, Chien-An Shih, Chun-Feng Huang, Eugene McCloskey, Joon-Kiong Lee, Swan Sim Yeap, Ching-Lung Cheung, Natthinee Charatcharoenwitthaya, Unnop Jaisamrarn, Vilai Kuptniratsaikul, Rong-Sen Yang, Sung-Yen Lin, Akira Taguchi, Satoshi Mori, Julie Li-Yu, Seng Bin Ang, Ding-Cheng Chan, Wai Sin Chan, Hou Ng, Jung-Fu Chen, Shih-Te Tu, Hai-Hua Chuang, Yin-Fan Chang, Fang-Ping Chen, Keh-Sung Tsai, Peter R Ebeling, Fernando Marin, Francisco Javier Nistal Rodríguez, Huipeng Shi, Kyu Ri Hwang, Kwang-Kyoun Kim, Yoon-Sok Chung, Ian R Reid, Manju Chandran, Serge Ferrari, E Michael Lewiecki, Fen Lee Hew, Lan T Ho-Pham, Tuan Van Nguyen, Van Hy Nguyen, Sarath Lekamwasam, Dipendra Pandey, Sanjay Bhadada, Chung-Hwan Chen, Jawl-Shan Hwang, Chih-Hsing Wu
OBJECTIVES: This study aimed to present the Asia-Pacific consensus on long-term and sequential therapy for osteoporosis, offering evidence-based recommendations for the effective management of this chronic condition. The primary focus is on achieving optimal fracture prevention through a comprehensive, individualized approach. METHODS: A panel of experts convened to develop consensus statements by synthesizing the current literature and leveraging clinical expertise...
March 2024: Osteoporosis and Sarcopenia
#25
JOURNAL ARTICLE
Sydney T Lam, Jonathan W Lam, Akshay J Reddy, Longines Lee, Zeyu Yu, Benjamin E Falkenstein, Victor W Fu, Evan Cheng, Rakesh Patel
This investigation explores the potential efficacy of machine learning algorithms (MLAs), particularly convolutional neural networks (CNNs), in distinguishing between benign and malignant breast cancer tissue through the analysis of 1000 breast cancer images gathered from Kaggle.com, a domain of publicly accessible data. The dataset was meticulously partitioned into training, validation, and testing sets to facilitate model development and evaluation. Our results reveal promising outcomes, with the developed model achieving notable precision (92%), recall (92%), accuracy (92%), sensitivity (89%), specificity (96%), an F1 score of 0...
March 2024: Curēus
#26
REVIEW
Abhishek Jain, Amol Singam, V N K Srinivas Mudiganti
Sepsis remains a critical healthcare challenge, characterized by dysregulated immune responses to infection, leading to organ dysfunction and high mortality rates. Traditional treatment strategies often fail to address the underlying immune dysregulation, necessitating exploring novel therapeutic approaches. Immunomodulatory therapy holds promise in sepsis management by restoring immune balance and mitigating excessive inflammation. This comprehensive review examines the pathophysiology of sepsis, current challenges in treatment, and recent advancements in immunomodulatory agents, including biologics, immunotherapy, and cellular therapies...
March 2024: Curēus
#27
REVIEW
Kathryn Jarvis, Clare Thetford, Edward Turck, Kelly Ogley, Rachel C Stockley
BACKGROUND: Digital Health technologies (DHT) have potential to deliver intensive, novel and engaging rehabilitation for people with neurological conditions, yet health services lack a strong track record in embedding DHT into practice. The aim of this review was to synthesise factors that have been shown to influence implementation of DHT into neurological rehabilitation. METHOD: An integrative review was undertaken. An extensive search of MEDLINE, CINAHL, AMED, EMBASE was undertaken...
2024: Health Services Insights
#28
REVIEW
Nawaf Almutairi
Pulp therapy aims to maintain the health and integrity of teeth and their supporting tissue and preserve the vitality of the tooth pulp affected by dentinal caries or severe traumatic injury. Thus, the best clinical practice provides pulpal health or pathosis diagnosis and various therapeutic interventions evidenced in both the deciduous and permanent dentition for endodontic treatment. The pulp health status determines the type of pulpal therapy used. Vital pulp therapies for primary teeth include protective liners, pulp capping, and pulpotomy for reversible pulpitis; for permanent teeth, pulpotomy can be considered for irreversible pulpitis...
April 2024: Saudi Dental Journal
#29
JOURNAL ARTICLE
Alexander Broll, Martin Rosentritt, Thomas Schlegl, Markus Goldhacker
BACKGROUND AND OBJECTIVE: Due to the high prevalence of dental caries, fixed dental restorations are regularly required to restore compromised teeth or replace missing teeth while retaining function and aesthetic appearance. The fabrication of dental restorations, however, remains challenging due to the complexity of the human masticatory system as well as the unique morphology of each individual dentition. Adaptation and reworking are frequently required during the insertion of fixed dental prostheses (FDPs), which increase cost and treatment time...
2024: Frontiers in artificial intelligence
#30
JOURNAL ARTICLE
Xiao-Pei Li, Zeng-Tao Bao, Li Wang, Chun-Yan Zhang, Wen Yang
BACKGROUND: Acute liver failure (ALF) is a common cause of postoperative death in patients with hepatocellular carcinoma (HCC) and is a serious threat to patient safety. The neutrophil-to-lymphocyte ratio (NLR) is a common inflammatory indicator that is associated with the prognosis of various diseases, and the albumin-bilirubin score (ALBI) is used to evaluate liver function in liver cancer patients. Therefore, this study aimed to construct a predictive model for postoperative ALF in HCC tumor integrity resection (R0) based on the NLR and ALBI, providing a basis for clinicians to choose appropriate treatment plans...
April 27, 2024: World Journal of Gastrointestinal Surgery
#31
MULTICENTER STUDY
Yan Liu, Bai-Jin-Tao Sun, Chuan Zhang, Bing Li, Xiao-Xuan Yu, Yong Du
BACKGROUND: Perineural invasion (PNI) has been used as an important pathological indicator and independent prognostic factor for patients with rectal cancer (RC). Preoperative prediction of PNI status is helpful for individualized treatment of RC. Recently, several radiomics studies have been used to predict the PNI status in RC, demonstrating a good predictive effect, but the results lacked generalizability. The preoperative prediction of PNI status is still challenging and needs further study...
April 28, 2024: World Journal of Gastroenterology: WJG
#32
JOURNAL ARTICLE
Niranjna Swaminathan, Wireko Andrew Awuah, Hareesha Rishab Bharadwaj, Sakshi Roy, Tomas Ferreira, Favour Tope Adebusoye, Isma Farah Nurlisa Binti Ismail, Saleha Azeem, Toufik Abdul-Rahman, Marios Papadakis
BACKGROUND AND AIMS: Diabetic Foot Ulcers (DFUs) are a significant health concern, particularly in Low- and Middle-Income Countries (LMICs). This review explores key strategies for managing DFUs in LMICs, including integrating podiatry, endocrinology, and wound care services, educating patients, promoting self-care, and preventive measures to reduce amputation rates. METHODS: A comprehensive literature review was conducted, focusing on studies conducted in Low and Middle Income Countries to facilitate a qualitative analysis...
May 2024: Health Science Reports
#33
JOURNAL ARTICLE
Kai J Wessel, Viola A Stögner, Catherine T Yu, Bohdan Pomahac, Tobias Hirsch, Haripriya S Ayyala, Maximilian Kueckelhaus
BACKGROUND: Recent advancements in the development of robotic devices increasingly draw the attention toward the concept of robotic microsurgery, as several systems tailored to open microsurgery are being introduced. This study describes the combined application of a novel microsurgical robot, the Symani, with a novel robotic microscope, the RoboticScope, for the performance of microvascular anastomoses in a two-center preclinical trial. METHODS: Six novices, residents, and experienced microsurgeons (n = 18) performed five anastomoses on 1...
April 2024: Plastic and Reconstructive Surgery. Global Open
#34
JOURNAL ARTICLE
Yanli Wu, Zhongwen Zhang, Qing Li, Xiu Yuan, Jiange Ren, Yulin Chen, He Zhu
OBJECTIVE: To evaluate the clinical effectiveness of combining postural control with electroacupuncture in the treatment of dysphagia following stroke, with the goal of establishing a solid clinical foundation for this therapeutic approach and investigating potential mechanisms to stimulate additional research and progress in post-stroke dysphagia management. METHODS: 138 patients who met the diagnostic and inclusion criteria were enrolled and divided into control group and observation group...
2024: Frontiers in Neurology
#35
REVIEW
C Berry-Kilgour, L Wise, J King, I Oey
Tissue engineering encompasses a range of techniques that direct the growth of cells into a living tissue construct for regenerative medicine applications, disease models, drug discovery, and safety testing. These techniques have been implemented to alleviate the clinical burdens of impaired healing of skin, bone, and other tissues. Construct development requires the integration of tissue-specific cells and/or an extracellular matrix-mimicking biomaterial for structural support. Production of such constructs is generally expensive and environmentally costly, thus eco-sustainable approaches should be explored...
2024: Frontiers in Bioengineering and Biotechnology
#36
REVIEW
Laura Fontana, Silvia M Sirchia, Chiara Pesenti, Giovanni Maria Colpi, Monica R Miozzo
Recent advancements in reproductive medicine have guided novel strategies for addressing male infertility, particularly in cases of non-obstructive azoospermia (NOA). Two prominent invasive interventions, namely testicular sperm extraction (TESE) and microdissection TESE (micro-TESE), have emerged as key techniques to retrieve gametes for assisted reproduction technologies (ART). Both heterogeneity and complexity of NOA pose a multifaceted challenge to clinicians, as the invasiveness of these procedures and their unpredictable success underscore the need for more precise guidance...
2024: Frontiers in Endocrinology
#37
REVIEW
Zhaokai Zhou, Ruiqi Zhang, Aoyang Zhou, Jinxiang Lv, Shuang Chen, Haijiao Zou, Ge Zhang, Ting Lin, Zhan Wang, Yuyuan Zhang, Siyuan Weng, Xinwei Han, Zaoqu Liu
Recent advances in high-throughput proteomic profiling technologies have facilitated the precise quantification of numerous proteins across multiple specimens concurrently. Researchers have the opportunity to comprehensively analyze the molecular signatures in plentiful medical specimens or disease pattern cell lines. Along with advances in data analysis and integration, proteomics data could be efficiently consolidated and employed to recognize precise elementary molecular mechanisms and decode individual biomarkers, guiding the precision treatment of tumors...
December 2024: Computational and Structural Biotechnology Journal
#38
JOURNAL ARTICLE
Karanjot Chhatwal, Alexander Deighton, Abhay Dhir, Varun Vijay Kumar, Sean Titus-Glover, Darsh Shah, Luke Holt
With health and surgery increasingly aided by digital technologies, there exists a growing impetus to understand how such tools must integrate into existing clinical pathways to ensure a positive impact on patient and organisational outcomes. Consequently, this study sought to collate evidence on the use of digital technology in cardiac reperfusion surgeries. We systematically searched three scientific databases for relevant articles. In total, 1,092 articles were retrieved, with 126 screened using inclusion/exclusion criteria, and 21 selected for analysis...
March 2024: Future Healthcare Journal
#39
REVIEW
Social support via Internet communication technology for diabetes self-management: a scoping review.
Danielle Hazime, Elizabeth Burner
BACKGROUND: The global prevalence of diabetes has been increasing over the past 30 years, leading to a rise in complications; diabetes is the leading cause of amputations, blindness, and kidney failure in developed countries. Diabetes self-management is challenging due to the complex lifestyle changes required. Social support from family and friends plays a crucial role in overcoming barriers to healthy behavior choices. Integrating Internet and communication technologies with social support interventions has the potential to improve diabetes self-management...
2024: MHealth
#40
JOURNAL ARTICLE
Nikola Kirilov
BACKGROUND: The integration of real-time data (RTD) in the electronic health records (EHRs) is transforming the healthcare of tomorrow. In this work, the common scenarios of capturing RTD in the healthcare from EHRs are studied and the approaches and tools to implement real-time solutions are investigated. METHODS: Delivering RTD by representational state transfer (REST) application programming interfaces (APIs) is usually accomplished through a Publish-Subscribe approach...
2024: MHealth
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